ABSTRACT

Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome is characterized by sudden onset of edema with swelling on the dorsum of the hands and by synovitis. Serological tests are negative and radiographic joint destruction does not occur. Etiology of RS3PE syndrome is not known. It can occur as an idiopathic phenomenon, but also is in association with rheumatic diseases, most frequently with late-onset rheumatoid arthritis and polymyalgia rheumatica. In addition, several reports have described RS3PE as a paraneoplastic syndrome can occur concomitantly with both hematological and solid malignancies. We aimed to present a RS3PE case in whom lung cancer was detected at clinical follow up. (Turkish Journal of Osteoporosis 2014;20: 89-91)