The aim of this study was to investigate the risk factors for osteoporotic vertebral fractures in postmenopausal women. 44 postmenopausal women whose L 2-L4 T scores were £ -2.5 SD with a mean age of 66.38+ 6.47 years were included in this study. Age, postmenopausal years, body mass index, milk consumption (before and after age 50), family history of osteoporosis and osteoporotic fracture, patient’s previous fracture history, tobacco use, number of pregnancies, surgical menopause were questioned in all patients. DEXA was used to evaluate bone mineral density . Kleerekoper method was used to evaluate the fractures between T4 and L5 vertebra on lateral thoracal and lumbar X rays.When 25 patient with vertebral fractures compared with 19 patients without fracture ,only patient’s age showed statistically significant difference between groups ( p=0.035). Of the 5 risk factors chosen (age, L2-L4 BMD, L2-L4 T score, body weight 57 kg, milk consumption before age 50) only patient’s age was found to be statistically important in estimating vertebral fracture risk (p=0.032).There was statistically significant positive correlation between vertebral deformity score (evaluated according to Kleerekoper method) and patient’s age and postmenopausal years (respectively p=0.001, p=0.006).Key words: Osteoporosis, vertebral fracture, risk factors
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GIRIS
Osteoporozla iliskili vertebral fraktürlü kadinlarin %30-50 sinde ciddi fonksiyonel kayiplar gözlenir. Son çalismalarda vertebral fraktürlerin; bel disabilitesinde artis, aktivitelerde kisitlanma, yataga bagimli kalma süresinde ve mortalitede artisa neden oldugu bildirilmistir. Mevcut vertebral fraktür gelecekte olusacak fraktürler için güçlü bir gösterge oldugundan ve yeni tedavilerle fraktür insidansi azaltilabileceginden risk altindaki hastalarin tanimlanmasi önem tasimaktadir (1). Kemik mineral yogunlugu (KMY) ölçümleri fraktür riskini tahmin etmede yaygin olarak kullanilmaktadir. Ayrica KMY ölçümlerinden bagimsiz olarak fraktür riskini arttirdigi bilinen bir çok diger risk faktörleri de belirlenmistir (2). Bu çalisma postmenopozal osteoporotik kadinlarda radyolojik vertebral fraktürü üzerine risk faktörlerinin etkisini arastirmak ve seçilen 5 risk faktörünün vertebral fraktür riskini kestirmedeki rolünü incelemek amaci ile yapilmistir.
