In this study the bone density of the upper femur and radius were compared accoding to the severity of knee osteoarthritis (OA), bone mineral index (BMI) and age. Eighty two postmenopausal women with knee osteoarthritis were recruited in this study. Bone mineral density of the femur and radius was measured using dual energy x-ray absorptiometry(DEXA). Radiological grading of knee OA was done by using Kellgren-Lawrence and individual feature scales. In our study, there were 15 subjects with Kellgren and Lawrence grade 0, 13 with grade 1, 21 with grade 2, 25 with grade 3, and 8 with grade 4 OA. There were no differences in hip and radius bone mineral density (BMD) by presence of any radiographic features of OA in patients (p0.05). BMD of the femoral neck and trochanter was significantly associated with BMI (p 0.01). Negative correlation was found between age and BMD (p 0.05). BMD was not associated with knee OA. With aging, we found a strong correlation between the femur BMD and BMI, although BMD decreased with age.Key words: Osteoporosis, knee osteoarthritis.
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GIRIS
Osteoartrit(OA) ve osteoporoz (OP) yasli nüfusun en önemli saglik problemleri arasinda yer alir. OA ve OP’un ayni kiside birlikte bulunmasi klinik tecrübelere göre nadir görülen bir durumdur. Yapilan birkaç epidemiyolojik çalismada OP’a bagli kalça kiriklarinda, OA görülme insidansi ve prevelansi düsük bulunmustur(1,2). Günümüzde OA ve OP arasinda zit iliski bulunduguna dair epidemiyolojik çalismalar ile de desteklenmis olan yaygin bir görüs vardir. Foss ve Byers(3) tarafindan zit iliskinin ortaya atildigi 1972 yilindan bu yana iki hastalik arasindaki iliski arastirilmaktadir. Bir iliski bulundugunda ise bunun siklikla zit iliski oldugu tespit edilmistir. Yani OA’de kemik kitlesi ve kemik dansitesi yüksek bulunmustur(1). Bununla birlikte bu konu henüz tam olarak aydinlatilamamistir.Bu çalismanin amaci, diz osteoartritinin radyografik degisiklikleri ile radius ve proksimal femur kemik mineral yogunluklari arasindaki iliskiyi incelemektir. Ayni zamanda yas ve vücut kitle indeksi(VKI) ile diz OA’nin radyografik bulgulari, radius ve femur kemik mineral yogunlugu (KMY) arasinda iliski olup olmadigi da arastirilmistir.
