Kraniyal ve Sakroiliak Tutulum ile Tanı Konulan Alkalen Fosfatazın Normal Olduğu Paget Hastalığı
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P: 136-138
Ağustos 2020

Kraniyal ve Sakroiliak Tutulum ile Tanı Konulan Alkalen Fosfatazın Normal Olduğu Paget Hastalığı

Turk J Osteoporos 2020;26(2):136-138
Bilgi mevcut değil.
Bilgi mevcut değil
Alındığı Tarih: 12.09.2019
Kabul Tarihi: 08.11.2019
Yayın Tarihi: 27.08.2020
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ÖZET

Kemiğin Paget hastalığı, genellikle radyolojik incelemelerde tesadüfen tespit edilen kronik fokal kemik yapılanma bozukluğu ile karakterizedir. Her ne kadar serum total alkalen fosfataz Paget hastalığında genel bir kemik döngüsü belirteci olsa da, hastaların yaklaşık %10-15’inde referans aralığında bulunur. Semptomatik formların tedavisi, kemik döngüsündeki yükselmeleri azaltmakta etkili olan bifosfonatlar ile sağlanır. Burada kronik bel ağrısı olan ve normal serum alkalen fosfataz ve kemik spesifik alkalen fosfataz düzeyleri ile Paget hastalığı tanısı alan 80 yaşında bir olgu sunulmaktadır.

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