ÖZET

Amaç:

Böbrek nakilli hastalarda obezite ile osteoporoz arasındaki ilişkiyi yeni bir antropometrik ölçüm olan “beden şekil indeksi (ABSI)” kullanarak araştırmayı amaçladık.

Gereç ve Yöntem:

Bu kesitsel çalışmaya, takip edilen 130 böbrek nakilli hasta alındı. Laboratuvar ve demografik bulgular, böbrek yetersizliği etiyolojisi, diyaliz süresi, donör tipi, nakil sonrası süre, ek hastalıklar, kadınlarda menopoz durumu, ilaçlar hasta dosyalarından kaydedildi. Boy, kilo, bel ve kalça çevresi de dosyalardan kaydedildi. ABSI, belirli bir formülle hesaplandı. Kemik mineral yoğunluğu (KMY), dual X-ışını absorpsiyometrisi kullanılarak ölçüldü. T-skoruna göre hastalar normal, osteopenik ve osteoporotik olarak üç gruba ayrıldı.

Bulgular:

KMY değerlerine göre 24 hasta (%18,5), normal 82 hasta (%63,1) osteopenik ve 24 hastada (%18,5) osteoporotikti. Vücut kitle indeksi ile lomber (r=0,294, p=0,002) ve femur T-skorları ile arasında pozitif korelasyon bulundu (r=0,216 p=0,024). Lomber T-skoru ile ABSI arasında negatif korelasyon bulundu (r=-0,237, p=0,014). ROC eğrileri, ABSI’nın her iki cinsiyette osteoporozu olan ve olmayan hastaları ayırt etmek için en uygun güce sahip olduğunu gösterdi.

Sonuç:

ABSI’nın, böbrek nakilli hastalarda osteoporozu tahmin etmede diğer antropometrik ölçümlere kıyasla daha değerli olduğu bulundu.

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Böbrek Nakilli Hastalarda Obezite ve Osteoporoz Arasındaki İlişkiyi En İyi Tahmin Eden Antropometrik Parametre

ÖZET

References