Öz
Amaç
Arteriyel sertlik birçok hastalığın teşhisi ve takibinde kullanılır. Osteoporoz ve ateroskleroz arasında belirli bir etkileşim olmasına rağmen, arteriyel sertlik ile osteoporoz arasındaki korelasyon henüz net olarak belirlenmemiştir ve önceki bulgular değişkendir. Bu çalışmada, osteoporozun teşhisi ve takibinde kullanılan laboratuvar değerleri ile arteriyel sertlik parametreleri arasında bir korelasyon olup olmadığını belirlemeyi amaçladık.
Gereç ve Yöntem
Olgular, dual X-ray absorbsiometri bulgularına göre osteopeni, osteoporoz ve kontrol grupları olarak kategorize edildi. Arteriyel sertlik parametreleri (uyum, diyastolik duvar gerilimi, elastik modül ve gerilebilirlik), 108 postmenopozal kadın (46 osteopeni, 38 osteoporoz ve 24 kontrol) için sonografik bulgulara (intima-media kalınlığı, sistolik çap ve diyastolik çap) dayanarak değerlendirildi. Osteoporozun teşhisi ve takibinde kullanılan laboratuvar bulguları ve enflamatuvar göstergeler kaydedildi. Gruplar bu parametrelere göre karşılaştırıldı.
Bulgular
İntima-media kalınlığı ve uyumun arteriyel sertlik parametreleri hasta ve kontrol grupları arasında önemli ölçüde farklıydı (sırasıyla p=0,003 ve p=0,034).
Sonuç
Osteoporozlu hastalarda arteriyel sertliğin görülme sıklığı, kolayca erişilebilen bir tanı aracı olan ultrasonografi kullanılarak gözlemlendiği gibi arttı. Hem osteoporoz hem de arteriyel sertlik olgularında enflamatuvar göstergeler artış gösterdi.
Anahtar Kelimeler: Anahtar kelimeler: Osteoporoz, arteriyel sertlik, enflamasyon
Kaynakça
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