Öz
Amaç:
Parathormon (PTH) düzeyi kanda çeşitli nedenlerle yükselir ve primer veya sekonder hiperparatiroidizm olarak adlandırılır. PTH yüksekliğinin etiyolojisini araştıran herhangi bir çalışma yoktur.
Gereç ve Yöntem:
Çalışmaya 1 yıllık süre içerisinde herhangi bir sebeple yapılan kan testlerinde saptanan PTH yüksek bulunmuş 137 hasta dahil edildi.
Bulgular:
Tüm hastaların 118’i (%86,1) kadın, 19’u (%13,9) erkekti. D vitamini eksikliği 88’inde (%64,2), primer hiperparatiroidizm (PHPT) 38’inde %27,7’sinde ailesel hipokalsiürik hiperkalsemi (AHH), 8’inde (%5,8) ve 3’ünde (%2,2) kronik böbrek yetmezliği (KBY) tespit edildi.
Sonuç:
D vitamini eksikliği, genel popülasyonda sık görülen bir hastalıktır ve bazen artan PTH düzeyi ile birlikte bulunur. Bu nedenle, PTH ilk test olarak okunduğu ve yüksek olduğu tespit edildiğinde D vitamini eksikliği akılda tutulmalıdır. PHPT, AHH ve KBY gibi diğer sebepler de araştırılmalıdır.
Anahtar Kelimeler: Parathormon, etiyolojik nedenler, D vitamin eksikliği
Kaynakça
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