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The Relationship of Lean Body Mass with Vitamin D Level and Physical Performance
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Original Investigation
VOLUME: 25 ISSUE: 1
P: 1-5
April 2019

The Relationship of Lean Body Mass with Vitamin D Level and Physical Performance

Turk J Osteoporos 2019;25(1):1-5
DOI: 10.4274/tod.galenos.2018.77699
Eylül Yağıcıbulut Eren 1
Selda Sarıkaya 2
Şenay Özdolap 2
1. Adana Numune Eğitim ve Araştırma Hastanesi, Fizik Tedavi ve Rehabilitasyon Kliniği, Adana, Türkiye
2. Zonguldak Bülent Ecevit Üniversitesi Tıp Fakültesi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Zonguldak, Türkiye
No information available.
No information available
Received Date: 08.10.2018
Accepted Date: 27.12.2018
Publish Date: 25.04.2019
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ABSTRACT

Objective:

In this study, it was aimed to investigate the association between vitamin D level, physical performance and lean body mass (LBM).

Materials and Methods:

A hundred female patients with 35-50 age range were included in the study. Patients’ demographic variables, height and weight measurements were recorded and body mass index (BMI) was calculated. Serum 25-hydroxyvitamin D (25(OH)D) samples were analyzed. Patients were divided into 2 groups according to 25(OH)D levels; patients with low vitamin D levels (group 1) and normal vitamin D levels (group 2). Both groups’ LBM was assessed by dual-energy X-ray absorptiometry and physical performance was assessed by 6-Minute Walk Test (6MWT).

Results:

Mean levels of 25(OH)D were found as 14.026±7.10 ng/mL in group 1 and 43.40±10.03 ng/mL in group 2. When the results of LBM were evaluated, the mean of group 1 was 35.48 (26.33-47.17) kg and the group 2 was 35.14 (29.23-53.65), and there was no statistically significant difference between the groups with regard to the mean of LBM (p=0.679). No statistically significant difference was determined in terms of 6-MWT (p=0.992). According to serum 25(OH)D level, group 1 was divided into three subgroups as follow; Group 1a: 25(OH)D<10 ng/dL, group 1b: 10.1≤ 25(OH)D≤ 20 ng/dL, and group 1c: 20.1≤25(OH)D≤29.9 ng/dL. When the three subgroups of group 1 (group 1a, 1b, and 1c) and group 2 compared, there was no statistically significant difference observed between the LBM and 6-MWT means (p=0.975; p=0.644).

Conclusion:

In this study, we could not determine a relationship between LBM and serum 25(OH)D level, and physical performance. In patients with same exclusion criteria, we believe that it is necessary the studies evaluating on the serum 25(OH)D levels along with genetic factors influencing the functions of vitamin D and also on the muscle quality along with muscle mass.

References

1
Akpınar P, Icagasioglu A. D vitamininin yaşam kalitesi ile ilişkisi. Türk Osteoporoz Dergisi 2012;18:13-8.
2
Boland RL. VDR activation of intracellular signaling pathways in skeletal muscle. Mol Cell Endocrinol 2011;347:11-6.
3
Wolf O, Strom H, Milbrink J, Larsson S, Mallmin H. Differences in hip bone mineral density may explain the hip fracture pattern in osteoarthritic hips. Acta Orthop 2009;80:308-13.
4
Kassab M, Shaban I, Mohammad K, Creedy DK. Prevalence of Hypovitaminosis D Among Jordanian Healthy Infants: A Descriptive Cross Sectional Study. J Pediatr Nurs 2016;31:e119-25.
5
Pfeifer M, Begerow B, Minne HW. Vitamin D and muscle function. Osteoporos Int 2002;13:187-94.
6
Ceglia L. Vitamin D and skeletal muscle tissue and function. Mol Aspects Med 2008;29:407-14.
7
Annweiler C, Beauchet O, Berrut G, Fantino B, Bonnefoy M, Herrmann FR, et al. Is there an association between serum 25-hydroxyvitamin D concentration and muscle strength among older women? Results from baseline assessment of the EPIDOS study. J Nutr Health Aging 2009;13:90-5.
8
Girgis CM, Clifton-Bligh RJ, Hamrick MW, Holick MF, Gunton JE. The roles of vitamin D in skeletal muscle: form, function, and metabolism. Endocr Rev 2013;34:33-83.
9
Halfon M, Phan O, Teta D. Vitamin D: a review on its effects on muscle strength, the risk of fall, and frailty. Biomed Res Int 2015;2015:953241.
10
Messina C, Monaco CG, Ulivieri FM, Sardanelli F, Sconfienza LM. Dual-energy X-ray absorptiometry body composition in patients with secondary osteoporosis. Eur J Radiol 2016;85:1493-8.
11
Kullberg J, Brandberg J, Angelhed JE, Frimmel H, Bergelin E, Strid L, et al. Whole-body adipose tissue analysis: comparison of MRI, CT and dual energy X-ray absorptiometry. Br J Radiol 2009;82:123-30.
12
Shepherd JA, Baim S, Bilezikian JP, Schousboe JT. Executive summary of the 2013 International Society for Clinical Densitometry Position Development Conference on Body Composition. J Clin Densitom 2013;16:489-95.
13
Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2011;96:1911-30.
14
Basaran S, Güzel R, Benlidayı C, Uysal F. Osteoporozda Vitamin D. Düzeyinin Yaşam kalitesi Üzerine Etkisi. Osteoporoz Dünyasından 2006;12:35-8.
15
Bischoff-Ferrari HA. The 25-hydroxyvitamin D threshold for better health. J Steroid Biochem Mol Biol 2007;103:614-9.
16
Beaudart C, Buckinx F, Rabenda V, Gillain S, Cavalier E, Slomian J, et al. The effects of vitamin D on skeletal muscle strength, muscle mass, and muscle power: a systematic review and meta-analysis of randomized controlled trials. J Clin Endocrinol Metab 2014;99:4336-45.
17
Wortsman J, Matsuoka LY, Chen TC, Lu Z, Holick MF. Decreased bioavailability of vitamin D in obesity. Am J Clin Nutr 2000;72:690-3.
18
Zhao J, Zhang Q, Zhang HM, Guo HX, Oste R, Hao LN, et al. [Body vitamin D content and its relationship with body composition of children in Huairou district of Beijing]. Zhonghua Liu Xing Bing Xue Za Zhi 2010;31:34-8.
19
Kremer R, Campbell PP, Reinhardt T, Gilsanz V. Vitamin D status and its relationship to body fat, final height, and peak bone mass in young women. J Clin Endocrinol Metab 2009;94:67-73.
20
Scott D, Ebeling PR, Sanders KM, Aitken D, Winzenberg T, Jones G. Vitamin d and physical activity status: associations with five-year changes in body composition and muscle function in community-dwelling older adults. J Clin Endocrinol Metab 2015;100:670-8.
21
Roth SM, Zmuda JM, Cauley JA, Shea PR, Ferrell RE. Vitamin D receptor genotype is associated with fat-free mass and sarcopenia in elderly men. J Gerontol A Biol Sci Med Sci 2004;59:10-5.
22
Bozsodi A, Boja S, Szilagyi A, Somhegyi A, Varga PP, Lazary A. Muscle strength is associated with vitamin D receptor gene variants. J Orthop Res 2016;34:2031-7.
23
Grundberg E, Brandstrom H, Ribom EL, Ljunggren O, Mallmin H, Kindmark A. Genetic variation in the human vitamin D receptor is associated with muscle strength, fat mass and body weight in Swedish women. Eur J Endocrinol 2004;150:323-8.
24
Geusens P, Vandevyver C, Vanhoof J, Cassiman JJ, Boonen S, Raus J. Quadriceps and grip strength are related to vitamin D receptor genotype in elderly nonobese women. J Bone Miner Res 1997;12:2082-8.
25
Zheng Y, Wang C, Zhang H, Shao C, Gao LH, Li SS, et al. Polymorphisms in Wnt signaling pathway genes are associated with peak bone mineral density, lean mass, and fat mass in Chinese male nuclear families. Osteoporos Int 2016;27:1805-15.
26
Patel HP, Al-Shanti N, Davies LC, Barton SJ, Grounds MD, Tellam RL, et al. Lean mass, muscle strength and gene expression in community dwelling older men: findings from the Hertfordshire Sarcopenia Study (HSS). Calcif Tissue Int 2014;95:308-16.
27
Vilaca KH, Alves NM, Carneiro JA, Ferriolli E, Lima NK, Moriguti JC. Body composition, muscle strength and quality of active elderly women according to the distance covered in the 6-minute walk test. Braz J Phys Ther 2013;17:289-96.
28
Grimaldi AS, Parker BA, Capizzi JA, Clarkson PM, Pescatello LS, White MC, et al. 25(OH) vitamin D is associated with greater muscle strength in healthy men and women. Med Sci Sports Exerc 2013;45:157-62.
29
Hamilton B, Whiteley R, Farooq A, Chalabi H. Vitamin D concentration in 342 professional football players and association with lower limb isokinetic function. J Sci Med Sport 2014;17:139-43.
30
Ozturk G, Uzun M, Öztürk Y, İnanır A. D vitamini eksikliği olan hastalarda kas performansının değerlendirilmesi: Ön çalışma. . Türk Osteoporoz Dergisi 2013;19:17-9.