Evaluation of Eye Findings in Fibromyalgia Patients
PDF
Cite
Share
Request
Original Investigation
P: 19-22
April 2019

Evaluation of Eye Findings in Fibromyalgia Patients

Turk J Osteoporos 2019;25(1):19-22
1. Aksaray Ünivesitesi Tıp Fakültesi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Aksaray, Türkiye
2. Aksaray Ünivesitesi Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, Aksaray, Türkiye
3. Bolu Abant İzzet Baysal Fiziksel Tıp ve Rehabilitasyon Eğitim ve Araştırma Hastanesi, Fiziksel Tıp ve Rehabilitasyon Kliniği, Bolu, Türkiye
No information available.
No information available
Received Date: 08.12.2018
Accepted Date: 21.01.2019
Publish Date: 25.04.2019
PDF
Cite
Share
Request

ABSTRACT

Objective:

Fibromyalgia (FM) is a rheumatic disease which exactly unknown etiology, causes widespread body pain. In FM patients, a large variety of ocular findings, especially dry eye, occur with and without other rheumatic diseases. These ocular findings may be the first findings to warn the clinician for diagnosis in rheumatic diseases. The aim of this study is to evaluate the eye findings as clinically in patients with FM.

Materials and Methods:

The patients of those between the ages of 18-75, who were admitted to the Aksaray University Training and Research Hospital, Physical Medicine and Rehabilitation Polyclinic and diagnosed with FM, and then examined in the Ophthalmology Polyclinic, were included in the study. Patients’ files were reviewed retrospectively. The clinical diagnosis, socio-demographic characteristics, ocular examination findings, history, family history and the results of the treatments were recorded. Those who had undergone eye surgery, rheumatologic disease, diabetic retinopathy, glaucoma, systemic infection, autoimmune disease, cerebrovascular disease, major depression, abnormal laboratory values, and history of malignancy, were not included in the study. The diagnosis of FM was determined according to the American College of Rheumatology updated in 2016.

Results:

The files of 94 patients who met the appropriate criteria were included in the study. The mean age of the patients was 38.2 (18-75), and 80 (85%) were female and 14 (15%) were male. According to the ocular findings, 57 patients (57.4%) had eye pain, 28.2% had redness, 26.9% had burning-stinging, 15.1% had turbidity, 6.3% had burring, and 3.7% had itching. Among the causes of eye pain were 49.1% dry eye, 24.6% refractive failure, 12.3% blepharitis, and 3.5% allergy, while no cause was found in 10.5%.

Conclusion:

In our study; it was detected that the patients with FM have a large extent of eye pain, and the most important cause of the eye pain was dry eye. The result of study shows that patients with FM may be accompanied by various ocular findings in addition to chronic widespread body pain and multidisciplinary approach is important in chronic diseases such as FM.

References

1
Bobrzyk M, Łabuzek K, Orski M, Tarnawska D, Okopień B. Ocular symptoms in rheumatic diseases. Pol Merkur Lekarski 2014;36:357-60.
2
Santoro FA, Huang J. Ocular involvement in cutaneous connective tissue disease Clin Dermatol 2016;34:138-45.
3
Generali E, Cantarini L, Selmi C. Ocular Involvement in Systemic Autoimmune Diseases. Clin Rev Allergy Immunol 2015;49:263-70.
4
Shtein RM, Harper DE, Pallazola V, Harte SE, Hussain M, Sugar A, et al. Discordant dry eye disease (an American Ophthalmological Society thesis). Trans Am Ophthalmol Soc 2016;114:T4.
5
Turkyilmaz K, Turkyilmaz AK, Kurt EE, Kurt A, Oner V. Dry eye in patients with fibromyalgia and its relevance to functional and emotional status. Cornea 2013;32:862-6.
6
Wolfe F, Ross K, Anderson J, Russell IJ, Hebert L. The prevalence and characteristics of fibromyalgia in the general population. Arthritis Rheum 1995;38:19-28.
7
Forseth KO, Gran JT, Husby G. A population study of the incidence of fibromyalgia among women aged 26-55 years. Br J Rheumatol 1997;36:1318-23.
8
Schuster AK, Wettstein M, Gerhardt A, Eich W, Bieber C, Tesarz J. Eye Pain and Dry Eye in Patients with Fibromyalgia. Pain Med 2018;19:2528-35.
9
Chen CH, Yang TY, Lin CL, Chen CS, Lin WM, Kuo CN, et al. Dry eye syndrome risks in patients with fibromyalgia: A national retrospective study. Medicine 2016;95:1-6.
10
Martin EG, Campayo JG, Guedea MP, Ascaso FJ, Roca M, Ruiz FG, et al. Fibromyalgia Is Correlated with Retinal Nerve Fiber Layer Thinning. PLoS One 2016;11:e0161574.
11
Bambo MP, Martin EG, Ruiz FG, Magallon R, Roca M, Campoya JG, et al. Study of perfusion changes in the optic disc of patients with fibromyalgia syndrome using new colorimetric analysis software. J Fr Ophtalmol 2015;38:580-7.
12
Vehof J, Sillevis Smitt-Kamminga N, Kozareva D, Nibourg SA, Hammond CJ. Clinical characteristics of dry eye patients with chronic pain syndromes. Am J Ophthalmol 2016;162:59-65.
13
Lee CJ, Levitt RC, Felix ER, Sarantopoulos CD, Galor A. Evidence that dry eye is a comorbid pain condition in a U.S. veteran population Pain reports 2017;2:e629.
14
Gunaydin I, Terhorst T, Eckstein A, Daikeler T, Kanz L, Kötter I. Assessment of keratoconjunctivitis sicca in patients with fibromyalgia: Results of a prospective study. Rheumatol Int 1999;19:7-9.
15
Gallar J, Morales C, Freire V, Acosta MC, Belmonte C, Duran JA. Decreased corneal sensitivity and tear production in fibromyalgia. Invest Ophthalmol Vis Sci 2009;50:4129-34.
16
Galor A, Levitt RC, Felix ER, Martin ER, Sarantopoulos CD. Neuropathic ocular pain: An important yet underevaluated feature of dry eye. Eye (Lond) 2015;29:301-12.
17
Vehof J, Kozareva D, Hysi PG, Harris J, Nessa A, Williams FK, et al. Relationship between dry eye symptoms and pain sensitivity. JAMA Ophthalmol 2013;131:1304-8.
18
Kaido M, Kawashima M, Ishida R, Tsubota K. Relationship of corneal pain sensitivity with dry eye symptoms in dry eye with short tear break-up time. Invest Ophthalmol Vis Sci 2016;57:914.
19
Kötter I, Neuscheler D, Günaydin I, Wernet D, Klein R. Is there a predisposition for the development of autoimmune diseases in patients with fibromyalgia? Retrospective analysis with long term follow-up. Rheumatol Int 2007;27:1031-9.
20
Enríquez-de-Salamanca A, Castellanos E, Stern ME, Fernández I, Carreño E, García-Vázquez C, et al. Tear cytokine and chemokine analysis and clinical correlations in evaporative-type dry eye disease. Mol Vis 2010;16:862-73.