ABSTRACT

Objective:

The aim of this study was to identify risk factors for the development of depression in patients with osteoporosis, and to measure the psychosocial effects to the change in quality of life.

Material and Methods:

125 patients with osteoporosis were included in the study. A questionnaire was completed which was including age, sex, marital status, education level, occupation, height, weight, alcohol use, smoking, physical activity level, milk consumption, previous fragility fracture of the patients. Bone mineral density of the lumbar spine and femoral neck were measured with DEXA. Back and lumbar compression fractures of the individuals were recorded by back and lumbar radiography. To evaluate back pain, Visual Analog Scale (VAS) was used. To assess depression in patients, Beck Depression Inventory (BDI) was used, and to assess the quality of life the European Council of Osteoporosis Quality of Life Questionnaire (QUALEFFO) was used.

Results:

125 patients were included in the study, 57 patients (45.6%) had depression and 68 patients (54.4%) had not depression. The average age, illiteracy status, reduced physical activity level were higher in the patients with depression than the patients without depression. Vertebral compression fracture, family history of fracture, fall predisposition, and osteopenia in the risk factors of osteoporosis were found statistically significantly higher in the group with depression than the group without depression. Both lumbar and femoral T and Z values, and VAS values were significantly higher in the patients with depression than the patients without depression (p<0.05). The total value and all sub-parameters of quality of life scale QUALEFFO were significantly higher in patients with depression than patients without depression (p<0.05). Positive significant correlation was found between BDI scores and sub-parameters of QUALEFFO scores (p<0.05).

Conclusion:

Depression in individuals with increased bone loss was shown to lead to a further decrease in the quality of life. (Turkish Journal of Osteoporosis 2013;19: 58-64)

Giris

Ilerleyen yasla birlikte kemik kaybinin ve depressif semptomlarin arttigi bilinmektedir. Zaman geçtikçe bu iki durumun birbiriyle iliskisi gündeme gelmistir. Peki depresyon mu artmis kemik kaybi için risk faktörüdür yoksa artmis kemik kaybi mi osteoporoz için risk faktörüdür? sorusu tam açikliga kavusturulamasa da net iliskileri birçok kez ortaya konulmustur (1-3). Bu çift yönlü iliskinin bir baska boyutu ise hem depresyon hem de osteoporoz bireyin yasam kalitesini kötülestirmektedir (2-4). Simdiye kadar ki bu konuda yapilmis çalismalarda arastirma örneklemini ya premenapozal ya da postmenapozal kadinlar olusturmaktaydi (2-4). Çalismamizin daha önceki çalismalardan farki her iki cinsiyette de hem depresyon ve osteoporozla iliskili faktörleri hem de depresyonun yasam kalitesine etkisini göstermesi olmustur. Çünkü bu çalismanin amaci osteoporozlu hastalarda depresyon gelisimi için risk faktörlerini belirlemek ve bu psikososyal degisimin yasam kalitesine etkisini ölçmekti.